2. Signaling Pathways
  3. PROTAC
  4. Ligands for E3 Ligase
  5. NEURL1B Isoform

NEURL1B

 

NEURL1B Related Products (1):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-182008
    NEURL1B-IN-1 3068938-30-4
    NEURL1B-IN-1 is a molecular glue-like NEURL1B degrader with a Kd value of 46.2 nM. NEURL1B-IN-1 binds to Arg422 within the NHR2 domain of NEURL1B, triggers its autoubiquitination and proteasomal degradation, disrupts its interaction with DLL1, and attenuates the Notch signaling pathway. NEURL1B-IN-1 induces cell cycle arrest and apoptosis, and inhibits migration of hepatocellular carcinoma cells. NEURL1B-IN-1 is applicable to research related to hepatocellular carcinoma.
    NEURL1B-IN-1